Cayman Chemical

Featured Items

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Soluble Epoxide Hydrolase

FABP4 Protein and Assays

4E-BP1 EIA Kits

His-Express Detection EIA Kit

Latrunculin A

HU-308

8-hydroxy-2-deoxy Guanosine EIA Kit

Prostaglandin D Synthase (lipocalin-type; human) EIA Kit

PAF Acetylhydrolase (human recombinant)

Apoptotic Blebs Assay Kit

New Products

FAAH Inhibitor Screening Assay Kit

Glycerol Cell-Based Assay Kit

In Vitro Angiogenesis Assay Kit

Liver X Receptor β Transcription Factor Assay Kit

CAY10574

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Recombinant Soluble Epoxide Hydrolase Enzymes

sEH Proteins—important mediators of hypertension and inflammation.

Cayman Chemical offers three new recombinant proteins important for the hydrolysis of epoxyeicosatrienoic acids (EETs).

All recombinant Soluble Epoxide Hydrolase proteins…

FABP4 Protein and Assays

FABP4—a new therapeutic target for obesity and diabetes

Cayman Chemical is a leading provider of high-purity, active Fatty Acid Binding Proteins. Contact our sales staff for quotations on bulk preparations of FABP4 and FABP4 assay kits for your drug discovery efforts.

All FABP4 products from Cayman Chemical…

4E-BP1 EIA Kits

4E-BP1—a key regulator of protein translation

Cayman's two new immunometric (i.e., sandwich) assays are designed to accurately detect human Phospho-Thr³⁷/Thr⁴⁶ 4E-BP1 and total 4E-BP1 in cell culture lysates.

Full information for 4E-BP1 EIA Kits...

His-Express Detection EIA Kit

• For the rapid screening of His-tagged recombinant proteins in cell lysates and affinity column fractions

• Use in place of SDS-PAGE for semi-quantitative results in just a few hours

Full information for His-Express Detection Kits...

07-02 · Latrunculin A New

An actin disruption agent

Latrunculin A is a bioactive 2-thiazolidinone macrolide derived from sponges that sequesters G-actin and prevents F-actin assembly. It binds monomeric actin with 1:1 stoichiometry and can be used to block actin polymerization both in vitro (Kd = 0.2 μM) and in cells …

Details for Latrunculin A...

03-16 · HU-308

A selective CB₂ receptor agonist

HU-308 is a potent, selective agonist for the peripheral cannabinoid (CB₂) receptor. The K_i for CB₁ is >10 µM, while the K_i for CB₂ is approximately 20 nM. When administered to whole animals, HU-308 elicits hypotensive, analgesic, and …

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05-21 · 8-hydroxy-2-deoxy Guanosine EIA Kit New

A competitive EIA for quantification of 8-OH-2dG

Cayman’s 8-OH-dG EIA is a competitive assay that can be used for the quantification of 8-OH-dG in urine, cell culture, plasma, and other sample matrices. The EIA utilizes an anti-mouse IgG-coated plate and a tracer consisting of an 8-OH-dG-enzyme conjugate. This …

Details for 8-hydroxy-2-deoxy Guanosine EIA Kit...

06-09 · Prostaglandin D Synthase (lipocalin-type; human) EIA Kit New Excl.

An immunometric EIA for use with human L-PGDS

Cayman’s Prostaglandin D Synthase (human lipocalin-type) (L-PGDS) EIA Kit is an immunometric (i.e., sandwich) EIA. The standard curve ranges from 0-100 ng/ml, with a limit of detection of 6 ng/ml. Inter- and intra-assay CV’s of less than 15% may be achieved …

Details for Prostaglandin D Synthase (lipocalin-type; human) EIA Kit...

06-19 · PAF Acetylhydrolase (human recombinant) New

Details for PAF Acetylhydrolase (human recombinant)...

02-29 · Apoptotic Blebs Assay Kit

Cayman’s Apoptotic Blebs Assay Kit employs a recombinant protein containing single-chain variable fragments (scFv) of D56R fused to the protein A domain B fraction as an antibody for apoptotic blebs. The protein A portion of this fusion protein is recognized and visualized by fluorescein-conjugated …

Details for Apoptotic Blebs Assay Kit...

09-05 · FAAH Inhibitor Screening Assay Kit New

A convenient fluorescence-based method for screening FAAH inhibitors

Cayman’s FAAH Inhibitor Screening Assay Kit provides a convenient fluorescence-based method for screening FAAH inhibitors. FAAH hydrolyzes AMC-arachidonoyl amide resulting in the release of the fluorescent product, 7-amino-4-methylcoumarin (AMC). The fluorophore can be easily analyzed …

Details for FAAH Inhibitor Screening Assay Kit...

09-05 · Glycerol Cell-Based Assay Kit New

Cayman’s Glycerol Cell-Based Assay Kit provides a convenient tool for studying triglyceride/fatty acid cycling and its regulation in adipocytes or hepatocytes. This kit will allow users to screen compounds involved in lipid storage and metabolism. Chloroquine is included in the kit as a positive control for …

Details for Glycerol Cell-Based Assay Kit...

09-05 · In Vitro Angiogenesis Assay Kit New

In vitro cell-based assays using calf pulmonary aortic endothelial (CPAE), human umbilical vein endothelial cells (HUVEC), or other endothelial cells grown on an extracellular matrix containing collagen are important tools for identifying factors that regulate angiogenesis. A …

Details for In Vitro Angiogenesis Assay Kit...

09-05 · Liver X Receptor β Transcription Factor Assay Kit New

96-Well assay for measurement of LXRβ

Cayman’s Liver X Receptor β Transcription Factor Assay Kit is a sensitive colorimetric method for detecting specific transcription factor binding activity from nuclear exctracts and whole cell lysates in a 96-well format.

Details for Liver X Receptor β Transcription Factor Assay Kit...

09-04 · CAY10574 New

A CDK2-cyclin E and CDK9 inhibitor

CAY10574 is a potent, selective inhibitor of CDK9 in vitro with an IC₅₀ value of 0.35 µM. It is also a competitive inhibitor of CDK2-cyclin E with respect to ATP, with K_i and IC₅₀ values of 13.3 and 20 µM, respectively. CAY10574 reduces the …

Details for CAY10574...

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